How do I remove 'com.wacom.DataStoreMgr.app' pop-up after Time Machine backup on Mac?

At this point I strongly recommend restoring a Time Machine backup created prior to actually using the aforementioned "cleaning" product. If you did not create a new set of backups for the Mac Studio yet, then you can always erase it and start over from the beginning, since you only recently did that. That will of course reintroduce the "damaged app" problem, but now you know how to uninstall it.

Having actually used "CleanMyMac" to alter that Mac's contents, you don't want the possibility of future problems hanging over your head for the life of your new Studio.

"Cleaning" apps are destructive in nature. It's what they do. Sometimes the incipient problems they create by deleting alleged "detritus" manifest long after they were used, completely and properly uninstalled, and perhaps long since forgotten about. The only practicable recourse in that event is to completely erase the Mac and reconfigure it from the ground up, or restore a TM backup created prior to using it. Your Studio is new, so either one of those choices are easy enough to do now.

Rule 1 of Macs is don't install junk.

Install and Un-Install

the fundamental principles:

• anything installed with drag-and-drop to the /Applications folder can be un-installed by Drag-and-drop to the Trash. After a Restart, the Trash can be emptied.

• anything installed with a complex installer program requires the manufacturer's un-installer program. sometimes this is included as an "option" in the Installer package, but the software-maker's web site should specify how to un-install (if they don't, they get swamped with users clamoring for Un-install Instructions)

• anything claiming to be an 'uninstaller helper' is just JUNK. (worse than web site click-bait)

NorfolkJak wrote:

All seems well. As a precaution I downloaded the app CleanMyMac and ran the free trial version, it’s amazing how much detritus there is!

Your problems have just begun.

several senior contributors refer to that software as "Brick My Mac". It does not have a good reputation, and should never be installed on a modern Mac.